Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei | |
Wang, Yilong1,2,3; Liu, Mei1,2; Wang, Baojie1,2; Jiang, Keyong1,2; Wang, Mengqiang1,2,4 ; Wang, Lei1,2,5
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| 2019-08-12 | |
| Source Publication | AQUACULTURE NUTRITION
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| ISSN | 1353-5773 |
| Pages | 13 |
| Corresponding Author | Wang, Mengqiang(wangmenggiang@qdio.ac.cn) ; Wang, Lei(wanglei@qdio.ac.cn) |
| Abstract | The present study was to determine the time-dependent alterations in growth performance, histomorphology, digestive enzymes activities and the genes expression related to target of rapamycin (TOR) signalling pathway involved in hepatopancreas and intestine of Litopenaeus vannamei at 3, 6, 12, 18, 24 and 30 days after Aflatoxin B1 (AFB1) challenge. The results manifested that AFB1 could induce a significant decrease in growth performance and visible variations of the hepatopancreas and intestine structures in shrimp. Meanwhile, the digestive enzymes activities and genes expression level were significantly lower in the experimental group than in the control group and showed a time-dependent decrease (p < 0.05). The expression levels of tor and s6k were significantly higher in the experimental group than in the control group from days 6 to 24 and showed a tendency to increase first and then decrease as a whole (p < 0.05). Meanwhile, we analysed candidate pathways involved in hepatopancreas and intestine of shrimp in metabolic response to AFB1. The mainly disturbed pathways related to metabolism in hepatopancreas were involved in pyrimidine, glycosylphosphatidylinositol, glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism, while the mainly disturbed metabolic pathways in intestine were glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism. |
| Keyword | aflatoxin B1 hepatopancreas intestinal Litopenaeus vannamei metabolism |
| DOI | 10.1111/anu.12956 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Major Scientific and Technological Innovation Project, Shandong Province, China[2018SDKJ0502-2] ; Science and Technology Development Fund Project of Shinan District, Qingdao City, China[2018-4-001-ZH] |
| WOS Research Area | Fisheries |
| WOS Subject | Fisheries |
| WOS ID | WOS:000481032400001 |
| Publisher | WILEY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/162349 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Wang, Mengqiang; Wang, Lei |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Natl Lab Marine Sci & Technol, Res Platform Marine Mol Biotechnol, Qingdao, Shandong, Peoples R China 5.Chinese Acad Sci, CAS Ctr Ocean Mega Sci, Qingdao, Shandong, Peoples R China |
| First Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Wang, Yilong,Liu, Mei,Wang, Baojie,et al. A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei[J]. AQUACULTURE NUTRITION,2019:13. |
| APA | Wang, Yilong,Liu, Mei,Wang, Baojie,Jiang, Keyong,Wang, Mengqiang,&Wang, Lei.(2019).A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei.AQUACULTURE NUTRITION,13. |
| MLA | Wang, Yilong,et al."A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei".AQUACULTURE NUTRITION (2019):13. |
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