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A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei
Wang, Yilong1,2,3; Liu, Mei1,2; Wang, Baojie1,2; Jiang, Keyong1,2; Wang, Mengqiang1,2,4; Wang, Lei1,2,5
2019-08-12
Source PublicationAQUACULTURE NUTRITION
ISSN1353-5773
Pages13
Corresponding AuthorWang, Mengqiang(wangmenggiang@qdio.ac.cn) ; Wang, Lei(wanglei@qdio.ac.cn)
AbstractThe present study was to determine the time-dependent alterations in growth performance, histomorphology, digestive enzymes activities and the genes expression related to target of rapamycin (TOR) signalling pathway involved in hepatopancreas and intestine of Litopenaeus vannamei at 3, 6, 12, 18, 24 and 30 days after Aflatoxin B1 (AFB1) challenge. The results manifested that AFB1 could induce a significant decrease in growth performance and visible variations of the hepatopancreas and intestine structures in shrimp. Meanwhile, the digestive enzymes activities and genes expression level were significantly lower in the experimental group than in the control group and showed a time-dependent decrease (p < 0.05). The expression levels of tor and s6k were significantly higher in the experimental group than in the control group from days 6 to 24 and showed a tendency to increase first and then decrease as a whole (p < 0.05). Meanwhile, we analysed candidate pathways involved in hepatopancreas and intestine of shrimp in metabolic response to AFB1. The mainly disturbed pathways related to metabolism in hepatopancreas were involved in pyrimidine, glycosylphosphatidylinositol, glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism, while the mainly disturbed metabolic pathways in intestine were glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism.
Keywordaflatoxin B1 hepatopancreas intestinal Litopenaeus vannamei metabolism
DOI10.1111/anu.12956
Indexed BySCI
Language英语
Funding ProjectMajor Scientific and Technological Innovation Project, Shandong Province, China[2018SDKJ0502-2] ; Science and Technology Development Fund Project of Shinan District, Qingdao City, China[2018-4-001-ZH]
WOS Research AreaFisheries
WOS SubjectFisheries
WOS IDWOS:000481032400001
PublisherWILEY
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/162349
Collection实验海洋生物学重点实验室
Corresponding AuthorWang, Mengqiang; Wang, Lei
Affiliation1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
4.Natl Lab Marine Sci & Technol, Res Platform Marine Mol Biotechnol, Qingdao, Shandong, Peoples R China
5.Chinese Acad Sci, CAS Ctr Ocean Mega Sci, Qingdao, Shandong, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wang, Yilong,Liu, Mei,Wang, Baojie,et al. A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei[J]. AQUACULTURE NUTRITION,2019:13.
APA Wang, Yilong,Liu, Mei,Wang, Baojie,Jiang, Keyong,Wang, Mengqiang,&Wang, Lei.(2019).A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei.AQUACULTURE NUTRITION,13.
MLA Wang, Yilong,et al."A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei".AQUACULTURE NUTRITION (2019):13.
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