Institutional Repository of Key Laboratory of Marine Ecology & Environmental Sciences, CAS
| Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China | |
Peng, Quancai1,2,3,4 ; Song, Jinming1,2,3,4; Li, Xuegang1,2,3,4; Yuan, Huamao1,2,3,4; Yang, Guang1,2,3,4
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| 2019-03-02 | |
| Source Publication | APPLIED SCIENCES-BASEL
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| Volume | 9Issue:6Pages:17 |
| Corresponding Author | Song, Jinming(jmsong@qdio.ac.cn) |
| Abstract | The occurrence and distribution of 110 pharmaceutically active compounds (PhACs) were investigated in snow near Jiaozhou Bay (JZB), North China. All target substances were analyzed using solid phase extraction followed by liquid chromatography coupled to tandem mass spectrometry.A total of 38 compounds were detected for the first time in snow, including 23 antibiotics, eight hormones, three nonsteroidal anti-inflammatory drugs, two antipsychotics, one beta-adrenergic receptor and one hypoglycemic drug. The total concentration of PhACs in snow ranged from 52.80 ng/L to 1616.02 ng/L. The compounds found at the highest mean concentrations included tetracycline (125.81 ng/L), desacetylcefotaxime (17.73 ng/L), ronidazole (8.79 ng/L) and triamcinolone diacetate (2.84 ng/L). The contribution of PhACs in the vicinity of JZB to the PhACs in the snow is far greater than the contribution of those transmitted over a long distance. PhACs are mainly derived from drugs applied to local humans and animals. Based on the individual risk quotient (RQ) values, tetracycline poses high risks to the relevant aquatic organisms (algae and invertebrates). The rational application and scientific management of PhACs is an effective approach to reduce the ecological risks in JZB. |
| Keyword | PhACs snow ecological risk Jiaozhou Bay (JZB) |
| DOI | 10.3390/app9061078 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Fund of the Key Science and Technology Innovation Program - Shandong Province ; Qingdao National Laboratory for Marine Science and Technology[2018SDKJ0504-1] ; National Natural Science Foundation of China[41676068] ; Development of Instrument & Equipment Function and Technical Innovation Project of CAS[HYQY-GNKF2016-1-2] ; Fund of the Key Science and Technology Innovation Program - Shandong Province ; Qingdao National Laboratory for Marine Science and Technology[2018SDKJ0504-1] ; National Natural Science Foundation of China[41676068] ; Development of Instrument & Equipment Function and Technical Innovation Project of CAS[HYQY-GNKF2016-1-2] |
| WOS Research Area | Chemistry ; Materials Science ; Physics |
| WOS Subject | Chemistry, Multidisciplinary ; Materials Science, Multidisciplinary ; Physics, Applied |
| WOS ID | WOS:000465017200043 |
| Publisher | MDPI |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/161256 |
| Collection | 海洋生态与环境科学重点实验室 |
| Corresponding Author | Song, Jinming |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Shandong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Ecol & Environm Sci, Qingdao 266237, Shandong, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Shandong, Peoples R China |
| First Author Affilication | Institute of Oceanology, Chinese Academy of Sciences; Center for Ocean Mega-Science, Chinese Academy of Sciences |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences; Center for Ocean Mega-Science, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Peng, Quancai,Song, Jinming,Li, Xuegang,et al. Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China[J]. APPLIED SCIENCES-BASEL,2019,9(6):17. |
| APA | Peng, Quancai,Song, Jinming,Li, Xuegang,Yuan, Huamao,&Yang, Guang.(2019).Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China.APPLIED SCIENCES-BASEL,9(6),17. |
| MLA | Peng, Quancai,et al."Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China".APPLIED SCIENCES-BASEL 9.6(2019):17. |
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| Characterization, So（2740KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View | |
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