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Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China
Peng, Quancai1,2,3,4; Song, Jinming1,2,3,4; Li, Xuegang1,2,3,4; Yuan, Huamao1,2,3,4; Yang, Guang1,2,3,4
2019-03-02
Source PublicationAPPLIED SCIENCES-BASEL
Volume9Issue:6Pages:17
Corresponding AuthorSong, Jinming(jmsong@qdio.ac.cn)
AbstractThe occurrence and distribution of 110 pharmaceutically active compounds (PhACs) were investigated in snow near Jiaozhou Bay (JZB), North China. All target substances were analyzed using solid phase extraction followed by liquid chromatography coupled to tandem mass spectrometry.A total of 38 compounds were detected for the first time in snow, including 23 antibiotics, eight hormones, three nonsteroidal anti-inflammatory drugs, two antipsychotics, one beta-adrenergic receptor and one hypoglycemic drug. The total concentration of PhACs in snow ranged from 52.80 ng/L to 1616.02 ng/L. The compounds found at the highest mean concentrations included tetracycline (125.81 ng/L), desacetylcefotaxime (17.73 ng/L), ronidazole (8.79 ng/L) and triamcinolone diacetate (2.84 ng/L). The contribution of PhACs in the vicinity of JZB to the PhACs in the snow is far greater than the contribution of those transmitted over a long distance. PhACs are mainly derived from drugs applied to local humans and animals. Based on the individual risk quotient (RQ) values, tetracycline poses high risks to the relevant aquatic organisms (algae and invertebrates). The rational application and scientific management of PhACs is an effective approach to reduce the ecological risks in JZB.
KeywordPhACs snow ecological risk Jiaozhou Bay (JZB)
DOI10.3390/app9061078
Indexed BySCI
Language英语
Funding ProjectFund of the Key Science and Technology Innovation Program - Shandong Province ; Qingdao National Laboratory for Marine Science and Technology[2018SDKJ0504-1] ; National Natural Science Foundation of China[41676068] ; Development of Instrument & Equipment Function and Technical Innovation Project of CAS[HYQY-GNKF2016-1-2]
WOS Research AreaChemistry ; Materials Science ; Physics
WOS SubjectChemistry, Multidisciplinary ; Materials Science, Multidisciplinary ; Physics, Applied
WOS IDWOS:000465017200043
PublisherMDPI
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/161256
Collection海洋生态与环境科学重点实验室
Corresponding AuthorSong, Jinming
Affiliation1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Shandong, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Ecol & Environm Sci, Qingdao 266237, Shandong, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Shandong, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Peng, Quancai,Song, Jinming,Li, Xuegang,et al. Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China[J]. APPLIED SCIENCES-BASEL,2019,9(6):17.
APA Peng, Quancai,Song, Jinming,Li, Xuegang,Yuan, Huamao,&Yang, Guang.(2019).Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China.APPLIED SCIENCES-BASEL,9(6),17.
MLA Peng, Quancai,et al."Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China".APPLIED SCIENCES-BASEL 9.6(2019):17.
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