IOCAS-IR  > 实验海洋生物学重点实验室
Trained Innate Immunity of Fish Is a Viable Approach in Larval Aquaculture
Zhang, Zuobing1; Chi, Heng2,3; Dalmo, Roy A.3
2019-01-25
Source PublicationFRONTIERS IN IMMUNOLOGY
ISSN1664-3224
Volume10Pages:5
Corresponding AuthorZhang, Zuobing(zbzhang@sxu.edu.cn) ; Chi, Heng(chiheng@qdio.ac.cn) ; Dalmo, Roy A.(roy.dalmo@uit.no)
AbstractThe general understanding has been that only adaptive immunity is capable of immunological memory, but this concept has been challenged in recent years by studies showing that innate immune systems can mount resistance to reinfection-as the innate immune system can adapt its function following an insult. Innate immune training offers an attractive approach in intensive fish larval rearing, especially since the adaptive immune system is not fully developed. Trained innate immunity will potentially favor robust fish in terms of resistance to viral and bacterial diseases. So-called immunostimulants such as beta-glucans have for decades been used both in laboratories and in intensive fish aquaculture. Treatment of fish by beta-glucans (and by other substances with pathogen-associated molecular patterns) often induces activation of non-specific/innate immune mechanisms and induces higher disease resistance. The reported effects of e.g., beta-glucans fit nicely into the concept "trained innate immunity," but the research on fish does not yet include analysis of epigenetic changes that may be a prerequisite for long-lasting trained innate immunity. In this "perspective," we will discuss how in practical terms and based on prior knowledge one can introduce innate immune training in brood stock fish, and their offspring, and whether innate immune training by beta-glucans is a viable approach in larval aquaculture.
Keywordtrained innate immunity aquaculture fish beta-glucan fish larvae
DOI10.3389/fimmu.2019.00042
Indexed BySCI
Language英语
Funding ProjectResearch Council of Norway[237315] ; Research Council of Norway[239140] ; University of Tromso (UIT The Arctic University of Norway Open Access publication Fund) ; Tromso Research Foundation
WOS Research AreaImmunology
WOS SubjectImmunology
WOS IDWOS:000456847600001
PublisherFRONTIERS MEDIA SA
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/160639
Collection实验海洋生物学重点实验室
Corresponding AuthorZhang, Zuobing; Chi, Heng; Dalmo, Roy A.
Affiliation1.Shanxi Univ, Sch Life Sci, Taiyuan, Shanxi, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China
3.Univ Tromso Arctic Univ Norway, Res Grp Aquaculture & Environm, Norwegian Coll Fishery Sci, Fac Biosci Fisheries & Econ, Tromso, Norway
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Zhang, Zuobing,Chi, Heng,Dalmo, Roy A.. Trained Innate Immunity of Fish Is a Viable Approach in Larval Aquaculture[J]. FRONTIERS IN IMMUNOLOGY,2019,10:5.
APA Zhang, Zuobing,Chi, Heng,&Dalmo, Roy A..(2019).Trained Innate Immunity of Fish Is a Viable Approach in Larval Aquaculture.FRONTIERS IN IMMUNOLOGY,10,5.
MLA Zhang, Zuobing,et al."Trained Innate Immunity of Fish Is a Viable Approach in Larval Aquaculture".FRONTIERS IN IMMUNOLOGY 10(2019):5.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhang, Zuobing]'s Articles
[Chi, Heng]'s Articles
[Dalmo, Roy A.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhang, Zuobing]'s Articles
[Chi, Heng]'s Articles
[Dalmo, Roy A.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhang, Zuobing]'s Articles
[Chi, Heng]'s Articles
[Dalmo, Roy A.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.