IOCAS-IR
Responses of Antioxidant Defense and Immune Gene Expression in Early Life Stages of Large Yellow Croaker (Pseudosciaena crocea) Under Methyl Mercury Exposure
Wu, Fangzhu1; Huang, Wei1; Liu, Qiang1; Xu, Xiaoqun1; Zeng, Jiangning1,2; Cao, Liang3; Hu, Ji1; Xu, Xudan1; Gao, Yuexin1; Jia, Shenghua1,4
2018-10-10
Source PublicationFRONTIERS IN PHYSIOLOGY
ISSN1664-042X
Volume9Pages:10
Corresponding AuthorHuang, Wei(huangwei8182@gmail.com)
AbstractEarly life stages of marine organisms are the most sensitive stages to environment stressors including pollutants. In order to understand the toxicological effects induced by MeHg exposure on juveniles of large yellow croaker (Pseudosciaena crocea), a toxicity test was performed wherein fish were exposed to sub-lethal concentrations of MeHg under laboratory conditions (18 +/- 1 degrees C; 26 +/- 1 in salinity). After 30 days of 0-4.0 mu g L-1 MeHg exposure, SOD activity was significantly decreased in the 0.25, 1.0, and 4.0 mu g L-1 treatments; while CAT activity was significantly increased in the 4.0 mu g L-1 treatments; GSH level, GPx activity were significantly elevated in the 4.0 mu g L-1 treatments, respectively. Meanwhile, malondialdehyde content was also significantly increased in the 1.0 and 4.0 mu g L-1 treatments with respect to the control. Acetylcholinesterase activity was significantly decreased by 18.3, 25.2, and 21.7% in the 0.25, 1.0, and 4.0 mu g L-1 treatments, respectively. The expression of TCTP, GST3, Hsp70, Hsp27 mRNA were all up-regulated in juveniles with a dose-dependent manner exposed to MeHg. These results suggest that large yellow croaker juveniles have the potential to regulate the levels of antioxidant enzymes and initiate immune response in order to protect fish to some extent from oxidative stress induced by MeHg.
Keywordlarge yellow croaker juvenile MeHg exposure antioxidant defense system mRNA expression
DOI10.3389/fphys.2018.01436
Indexed BySCI
Language英语
Funding ProjectNational Marine Public Welfare Research Project of China[201405007] ; National Natural Science Foundation of China[41306112] ; National Natural Science Foundation of China[41406167] ; National Natural Science Foundation of China[21307019] ; China-APEC Cooperation Fund[2029901] ; Science and Technology Support Program of China[2015BAD08B01] ; Basic Scientific Research of SIO, China[JG1717] ; Basic Scientific Research of SIO, China[JG1526]
WOS Research AreaPhysiology
WOS SubjectPhysiology
WOS IDWOS:000446897000001
PublisherFRONTIERS MEDIA SA
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/160396
Collection中国科学院海洋研究所
Corresponding AuthorHuang, Wei
Affiliation1.State Ocean Adm, Inst Oceanog 2, Key Lab Marine Ecosyst & Biogeochem, Hangzhou, Zhejiang, Peoples R China
2.Zhejiang Univ, Ocean Coll, Hangzhou, Zhejiang, Peoples R China
3.Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China
4.Zhejiang Surveying Inst Estuary & Coast, Hangzhou, Zhejiang, Peoples R China
Recommended Citation
GB/T 7714
Wu, Fangzhu,Huang, Wei,Liu, Qiang,et al. Responses of Antioxidant Defense and Immune Gene Expression in Early Life Stages of Large Yellow Croaker (Pseudosciaena crocea) Under Methyl Mercury Exposure[J]. FRONTIERS IN PHYSIOLOGY,2018,9:10.
APA Wu, Fangzhu.,Huang, Wei.,Liu, Qiang.,Xu, Xiaoqun.,Zeng, Jiangning.,...&Jia, Shenghua.(2018).Responses of Antioxidant Defense and Immune Gene Expression in Early Life Stages of Large Yellow Croaker (Pseudosciaena crocea) Under Methyl Mercury Exposure.FRONTIERS IN PHYSIOLOGY,9,10.
MLA Wu, Fangzhu,et al."Responses of Antioxidant Defense and Immune Gene Expression in Early Life Stages of Large Yellow Croaker (Pseudosciaena crocea) Under Methyl Mercury Exposure".FRONTIERS IN PHYSIOLOGY 9(2018):10.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wu, Fangzhu]'s Articles
[Huang, Wei]'s Articles
[Liu, Qiang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wu, Fangzhu]'s Articles
[Huang, Wei]'s Articles
[Liu, Qiang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wu, Fangzhu]'s Articles
[Huang, Wei]'s Articles
[Liu, Qiang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.