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Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity
Jin, Weihua1; Ren, Langlang1; Liu, Bing1; Zhang, Quanbin2,3; Zhong, Weihong1
2018-09-01
发表期刊MARINE DRUGS
ISSN1660-3397
卷号16期号:9页码:12
通讯作者Zhang, Quanbin(qbzhang@qdio.ac.cn) ; Zhong, Weihong(whzhong@zjut.edu.cn)
摘要Glucuronomannan oligosaccharides (Gs) were derived from fucoidan, which was extracted from the brown alga Sargassum thunbergii. Sulfated glucuronomannan oligosaccharides (SGs) were obtained by the sulfation of Gs. NMR techniques were used to reveal that the order of sulfation was Man-C6 > Man-C4 > Man-C1R > GlcA-C3 > Man-C3 > GlcA-C2. Finally, the antioxidant activities (hydroxyl radical scavenging activity, superoxide radical scavenging activity, reducing power and DPPH radical scavenging activity) of Gs and SGs were determined. The findings showed that the higher the degree of polymerization, the better the activity, except for the hydroxyl radical scavenging activity. In addition, the higher the sulfate content, the lower the activities for the reducing power and DPPH radical scavenging activity. Opposite results were found for the superoxide radical scavenging activity. Finally, compared with fucoidan, most Gs and SGs had higher antioxidant activity, suggesting that they might be good candidates for antioxidants.
关键词glucuronomannan oligosaccharides sulfation antioxidant activity
DOI10.3390/md16090291
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal
WOS记录号WOS:000445636600002
出版者MDPI
引用统计
被引频次:24[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/160386
专题实验海洋生物学重点实验室
通讯作者Zhang, Quanbin; Zhong, Weihong
作者单位1.Zhejiang Univ Technol, Coll Biotechnol & Bioengn, Hangzhou 310023, Zhejiang, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Lab Expt Marine Biol, Qingdao 266071, Peoples R China
3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266000, Peoples R China
通讯作者单位中国科学院海洋研究所
推荐引用方式
GB/T 7714
Jin, Weihua,Ren, Langlang,Liu, Bing,et al. Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity[J]. MARINE DRUGS,2018,16(9):12.
APA Jin, Weihua,Ren, Langlang,Liu, Bing,Zhang, Quanbin,&Zhong, Weihong.(2018).Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity.MARINE DRUGS,16(9),12.
MLA Jin, Weihua,et al."Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity".MARINE DRUGS 16.9(2018):12.
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