Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity | |
| Jin, Weihua1; Ren, Langlang1; Liu, Bing1; Zhang, Quanbin2,3; Zhong, Weihong1 | |
| 2018-09-01 | |
| Source Publication | MARINE DRUGS
 |
| ISSN | 1660-3397 |
| Volume | 16Issue:9Pages:12 |
| Corresponding Author | Zhang, Quanbin(qbzhang@qdio.ac.cn) ; Zhong, Weihong(whzhong@zjut.edu.cn) |
| Abstract | Glucuronomannan oligosaccharides (Gs) were derived from fucoidan, which was extracted from the brown alga Sargassum thunbergii. Sulfated glucuronomannan oligosaccharides (SGs) were obtained by the sulfation of Gs. NMR techniques were used to reveal that the order of sulfation was Man-C6 > Man-C4 > Man-C1R > GlcA-C3 > Man-C3 > GlcA-C2. Finally, the antioxidant activities (hydroxyl radical scavenging activity, superoxide radical scavenging activity, reducing power and DPPH radical scavenging activity) of Gs and SGs were determined. The findings showed that the higher the degree of polymerization, the better the activity, except for the hydroxyl radical scavenging activity. In addition, the higher the sulfate content, the lower the activities for the reducing power and DPPH radical scavenging activity. Opposite results were found for the superoxide radical scavenging activity. Finally, compared with fucoidan, most Gs and SGs had higher antioxidant activity, suggesting that they might be good candidates for antioxidants. |
| Keyword | glucuronomannan oligosaccharides sulfation antioxidant activity |
| DOI | 10.3390/md16090291 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Pharmacology & Pharmacy |
| WOS Subject | Chemistry, Medicinal |
| WOS ID | WOS:000445636600002 |
| Publisher | MDPI |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/160386 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Zhang, Quanbin; Zhong, Weihong |
| Affiliation | 1.Zhejiang Univ Technol, Coll Biotechnol & Bioengn, Hangzhou 310023, Zhejiang, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266000, Peoples R China |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Jin, Weihua,Ren, Langlang,Liu, Bing,et al. Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity[J]. MARINE DRUGS,2018,16(9):12. |
| APA | Jin, Weihua,Ren, Langlang,Liu, Bing,Zhang, Quanbin,&Zhong, Weihong.(2018).Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity.MARINE DRUGS,16(9),12. |
| MLA | Jin, Weihua,et al."Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity".MARINE DRUGS 16.9(2018):12. |
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