Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups | |
Liu, Weixiang1,2,3,4; Qin, Yukun1,2,3; Liu, Song1,2,3; Xing, Ronge1,2,3 ; Yu, Huahua1,2,3; Chen, Xiaolin1,2,3; Li, Kecheng1,2,3; Li, Pengcheng1,2,3
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| 2018-07-15 | |
| Source Publication | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| ISSN | 0141-8130 |
| Volume | 114Pages:942-949 |
| Corresponding Author | Qin, Yukun(ykqin@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn) |
| Abstract | A novel type of water soluble chitosan derivatives (TQCSPX) were synthesized including 3-aminopyridine (TQCSPI) and 3-Amino-4-methylpyridine (TQCSP2). The theoretical structures of TQCSPX were calculated by Gaussian 09 and confirmed by FT-IR, H-1 NMR, C-13 NMR, elemental analysis and XRD. The antifungal properties of TQCSPX against Phytophthora capsici (P. capsici), Rhizoctonia solani (R. solani), Fusarium oxysporum (F. oxysporum) and Fusarium solani (F. solani) were evaluated at concentrations ranging from 0.2 mg/mL to 0.8 mg/mL Antifungal results indicated that the derivatives have significantly enhanced antifungal activity after quaternized compared with the original chitosan (CS). Moreover, TQCSPI inhibited the growth of P. capsici with inhibitory indices of 91.94% at 0.8 mg/mL The experimental results demonstrated that the increasing number of the positive charge would improve the antifungal efficiency of chitosan, which may provide a novel direction for the development of fungicides. (C) 2018 Elsevier B.V. All rights reserved. |
| Keyword | Quaternized chitosan Aminopyridine Antifungal |
| DOI | 10.1016/j.ijbiomac.2018.03.179 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[41306071] ; Scientific and Technological Innovation Project - Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Science and Technology Program - Qingdao[17-3-3-60-nsh] |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
| WOS Subject | Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science |
| WOS ID | WOS:000435056900108 |
| Publisher | ELSEVIER SCIENCE BV |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/159407 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Qin, Yukun; Li, Pengcheng |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| First Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Liu, Weixiang,Qin, Yukun,Liu, Song,et al. Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,114:942-949. |
| APA | Liu, Weixiang.,Qin, Yukun.,Liu, Song.,Xing, Ronge.,Yu, Huahua.,...&Li, Pengcheng.(2018).Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,114,942-949. |
| MLA | Liu, Weixiang,et al."Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 114(2018):942-949. |
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| Synthesis, character（1740KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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