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| New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535 | |
Yang, Sui-Qun1,2,3; Li, Xiao-Ming1,2; Li, Xin1,2 ; Li, Hong-Lei1,2; Meng, Ling-Hong1,2; Wang, Bin-Gui1,2
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| 2018-06-01 | |
| 发表期刊 | PHYTOCHEMISTRY LETTERS
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| ISSN | 1874-3900 |
| 卷号 | 25页码:191-195 |
| 通讯作者 | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) |
| 摘要 | Ten citrinin analogues (1-10), including a new citrinin dimer (seco-penicitrinol A, 2) and a new citrinin monomer (penicitrinol L, 3), were isolated from the EtOAc extracts of the coculture of two marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535. Their structures were elucidated by detailed analysis of their NMR spectra, ECDs, HRESIMS, optical rotation, and X-ray crystallographic data, and by comparison with literature data as well. The crystal structure of compound 1 was reported for the first time in this paper and resulted in unambiguous confirmation of its absolute configuration as 3R, 4S, 2'R, and 3'S, while the absolute configuration of compound 3 was determined by TDDFT calculations of its ECD spectrum. The antimicrobial and influenza neuraminidase inhibitory activities of compounds 1-10 were evaluated. |
| 关键词 | Coculture Aspergillus sydowii Penicillium citrinum Citrinin analogue Antimicrobial activity Influenza neuraminidase inhibitory activity |
| DOI | 10.1016/j.phytol.2018.04.023 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | Natural Science Foundation of China (NSFC)[31330009] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar Project from Shandong Province of China ; Natural Science Foundation of China (NSFC)[31330009] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar Project from Shandong Province of China |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| WOS类目 | Plant Sciences ; Chemistry, Medicinal |
| WOS记录号 | WOS:000433356000039 |
| 出版者 | ELSEVIER SCIENCE BV |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/159243 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Nanhai Rd 7, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 通讯作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Yang, Sui-Qun,Li, Xiao-Ming,Li, Xin,et al. New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535[J]. PHYTOCHEMISTRY LETTERS,2018,25:191-195. |
| APA | Yang, Sui-Qun,Li, Xiao-Ming,Li, Xin,Li, Hong-Lei,Meng, Ling-Hong,&Wang, Bin-Gui.(2018).New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535.PHYTOCHEMISTRY LETTERS,25,191-195. |
| MLA | Yang, Sui-Qun,et al."New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535".PHYTOCHEMISTRY LETTERS 25(2018):191-195. |
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| New citrinin analogu（705KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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