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Comparative sensitivity of the hepatopancreas and midgut in the white shrimp Litopenaeus vannamei to oxidative stress under cyclic serious/medium hypoxia
Han, Si-yin1,2,3; Wang, Meng-qiang1,2; Liu, Mei1,2; Wang, Bao-jie1,2; Jiang, Ke-yong1,2; Wang, Lei1,2
2018-03-01
Source PublicationAQUACULTURE
ISSN0044-8486
Volume490Pages:44-52
Corresponding AuthorWang, Lei(wanglei@qdio.ac.cn)
AbstractLow dissolved oxygen (DO) could cause a stress response in shrimp, the objective of this study was to compare sensitivity of the hepatopancreas and midgut to oxidative stress under low DO. The white shrimp Litopenaeus vannamei were reared under conditions of cyclic serious/medium hypoxia (CSMH, 0.8-3.5 mg/L) versus normoxia (N, 6.4-7.5 mg/L) for a 28-day period. Survival and growth performance of shrimp were evaluated, and hypoxia inducible factors 1a (HIF-1 alpha) expression, antioxidant responses, apoptosis and histology in the hepatopancreas and midgut were investigated. Antioxidant responses tested included the following: manganese superoxide dismutase, glutathione peroxidases, glutathione-S-transferase, metallothionein and heat shock protein70 expression. Results showed enhanced HIF-1 alpha expression and antioxidant responses in the hepatopancreas and midgut during short-term cyclic serious/medium hypoxia (<= 7 days), which suggested early adaptive mechanism of shrimp to tolerate low DO and avoid oxidative damage. Meanwhile, HIF-1 alpha expression, apoptosis and histopathological lesions were induced earlier in the hepatopancreas than the midgut. Thus, the hepatopancreas could be more sensitive to low DO and its oxidative stress than the midgut. However, long-term (>= 14 days) cyclic serious/medium hypoxia could disrupt cellular antioxidant mechanism with depressed antioxidant responses, and then aggravate apoptosis and histopathological lesions in the hepatopancreas and midgut, particularly the hepatopancreas would lose antioxidant ability earlier than the midgut because of higher sensitivity to oxidative stress. Therefore, we have a few insights that it is vital to protect hepatopancreas for controlling shrimp death and growth inhibition under cyclic serious/medium hypoxia.
KeywordLitopenaeus vannamei Hepatopancreas Midgut Cyclic serious/medium hypoxia Oxidative stress Gene expression
DOI10.1016/j.aquaculture.2018.02.021
Indexed BySCI
Language英语
Funding ProjectSTS Key Deployment Project of Chinese Academy of Sciences[KFZD-SW-106]
WOS Research AreaFisheries ; Marine & Freshwater Biology
WOS SubjectFisheries ; Marine & Freshwater Biology
WOS IDWOS:000429323600007
PublisherELSEVIER SCIENCE BV
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/158803
Collection实验海洋生物学重点实验室
Corresponding AuthorWang, Lei
Affiliation1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China
3.Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 100049, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Han, Si-yin,Wang, Meng-qiang,Liu, Mei,et al. Comparative sensitivity of the hepatopancreas and midgut in the white shrimp Litopenaeus vannamei to oxidative stress under cyclic serious/medium hypoxia[J]. AQUACULTURE,2018,490:44-52.
APA Han, Si-yin,Wang, Meng-qiang,Liu, Mei,Wang, Bao-jie,Jiang, Ke-yong,&Wang, Lei.(2018).Comparative sensitivity of the hepatopancreas and midgut in the white shrimp Litopenaeus vannamei to oxidative stress under cyclic serious/medium hypoxia.AQUACULTURE,490,44-52.
MLA Han, Si-yin,et al."Comparative sensitivity of the hepatopancreas and midgut in the white shrimp Litopenaeus vannamei to oxidative stress under cyclic serious/medium hypoxia".AQUACULTURE 490(2018):44-52.
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