Synthesis, characterization, and antifungal evaluation of diethoxyphosphoryl polyaminoethyl chitosan derivatives

doi:10.1016/j.carbpol.2018.02.056

IOCAS-IR > 实验海洋生物学重点实验室

	Synthesis, characterization, and antifungal evaluation of diethoxyphosphoryl polyaminoethyl chitosan derivatives
	Fan, Zhaoqian 1,2,3; Qin, Yukun 1,2; Liu, Song 1,2; Xing, Ronge1,2 ; Yu, Huahua1,2 ; Chen, Xiaolin 1,2; Li, Kecheng 1,2; Li, Pengcheng1,2
	2018-06-15
发表期刊	CARBOHYDRATE POLYMERS
ISSN	0144-8617
卷号	190 页码:1-11
通讯作者	Qin, Yukun(ykqin@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn)
摘要	Botrytis cinerea, Phytophthora capsici Leonian, and Fusarium solani are important plant pathogenic fungi which can cause great crop losses worldwide, but their control methods are limited. It is necessary to develop efficient and green fungicides from abundant marine resources. Chitosan is a non-toxic, biodegradable, biocompatible marine polysaccharide which has prospective applications in agriculture. In this paper, to increase the antifungal activity of chitosan for application, novel water-soluble functional chitosan derivatives were synthesized by grafting polyaminoethyl and diethoxyphosphoryl groups in accordance with a strategy of improving protonation potential. The derivatives were characterized by FTIR, NMR, XRD, SEM, Gaussian 09 and elemental analysis. The antifungal activities against the three fungi and the cytotoxicity were estimated in vitro. The results showed that the derivatives had better antifungal activities and water solubility than chitosan, and had good biocompatibility. They confirmed that these chitosan derivatives can be developed as antifungal agents for plant protection purposes.
关键词	Chitosan Polyaminoethyl Phosphoryl Antifungal
DOI	10.1016/j.carbpol.2018.02.056
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41306071] ; Scientific and Technological Innovation Project - Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Public Science and Technology Research Funds Projects of Ocean[201305016-2] ; Public Science and Technology Research Funds Projects of Ocean[201405038-2] ; CAS STS Program[KFJ-SW-STS-143] ; National Natural Science Foundation of China[41306071] ; Scientific and Technological Innovation Project - Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Public Science and Technology Research Funds Projects of Ocean[201305016-2] ; Public Science and Technology Research Funds Projects of Ocean[201405038-2] ; CAS STS Program[KFJ-SW-STS-143]
WOS研究方向	Chemistry ; Polymer Science
WOS类目	Chemistry, Applied ; Chemistry, Organic ; Polymer Science
WOS记录号	WOS:000429425500001
出版者	ELSEVIER SCI LTD
引用统计	被引频次：67[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/158747
专题	实验海洋生物学重点实验室
通讯作者	Qin, Yukun; Li, Pengcheng
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Fan, Zhaoqian,Qin, Yukun,Liu, Song,et al. Synthesis, characterization, and antifungal evaluation of diethoxyphosphoryl polyaminoethyl chitosan derivatives[J]. CARBOHYDRATE POLYMERS,2018,190:1-11.
APA	Fan, Zhaoqian.,Qin, Yukun.,Liu, Song.,Xing, Ronge.,Yu, Huahua.,...&Li, Pengcheng.(2018).Synthesis, characterization, and antifungal evaluation of diethoxyphosphoryl polyaminoethyl chitosan derivatives.CARBOHYDRATE POLYMERS,190,1-11.
MLA	Fan, Zhaoqian,et al."Synthesis, characterization, and antifungal evaluation of diethoxyphosphoryl polyaminoethyl chitosan derivatives".CARBOHYDRATE POLYMERS 190(2018):1-11.

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