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The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri
Wang, Mengqiang1; Wang, Lingling2,3; Jia, Zhihao1,4; Yi, Qilin3; Song, Linsheng2,3
2018-03-01
Source PublicationFISH & SHELLFISH IMMUNOLOGY
ISSN1050-4648
Volume74Pages:205-212
Corresponding AuthorSong, Linsheng(lshsong@dlou.edu.cn)
AbstractToll-like receptor (TLR) signaling pathway, composed of various components, plays pivotal roles in host innate immune defense mechanism. In the present study, twenty-nine TLR signaling pathway components, including receptors, adaptors, transduction molecules and immune effectors, were identified in Zhikong scallop Chlamys farreri via assembling and screening public available transcriptomic data and expression sequence tags (ESTs). These identified TLR signaling pathway components were constitutively expressed and detectable in various tissues, and almost all of them were highly expressed in gill and hepatopancreas. These results indicated the presence of TLR signaling pathways in both MyD88-dependent and MyD88-independent forms in scallop, and implied the diversified TLR signaling pathway in mollusk C. farreri.
KeywordChlamys farreri Innate immunity TLR signaling pathway
DOI10.1016/j.fsi.2017.12.064
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[31530069] ; National Natural Science Foundation of China[41306156] ; AoShan Talents Cultivation Program ; Qingdao National Laboratory for Marine Science and Technology[2017ASTCP-OS13] ; Modern Agro-industry Technology Research System[CARS-49]
WOS Research AreaFisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences
WOS SubjectFisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences
WOS IDWOS:000427344200022
PublisherACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/158388
Collection实验海洋生物学重点实验室
Corresponding AuthorSong, Linsheng
Affiliation1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Funct Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China
3.Dalian Ocean Univ, Liaoning Key Lab Marine Anim Immunol, Dalian 116023, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
First Author AffilicationKey Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wang, Mengqiang,Wang, Lingling,Jia, Zhihao,et al. The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri[J]. FISH & SHELLFISH IMMUNOLOGY,2018,74:205-212.
APA Wang, Mengqiang,Wang, Lingling,Jia, Zhihao,Yi, Qilin,&Song, Linsheng.(2018).The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri.FISH & SHELLFISH IMMUNOLOGY,74,205-212.
MLA Wang, Mengqiang,et al."The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri".FISH & SHELLFISH IMMUNOLOGY 74(2018):205-212.
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