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| The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri | |
Wang, Mengqiang1 ; Wang, Lingling2,3; Jia, Zhihao1,4; Yi, Qilin3; Song, Linsheng2,3
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| 2018-03-01 | |
| Source Publication | FISH & SHELLFISH IMMUNOLOGY
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| ISSN | 1050-4648 |
| Volume | 74Pages:205-212 |
| Corresponding Author | Song, Linsheng(lshsong@dlou.edu.cn) |
| Abstract | Toll-like receptor (TLR) signaling pathway, composed of various components, plays pivotal roles in host innate immune defense mechanism. In the present study, twenty-nine TLR signaling pathway components, including receptors, adaptors, transduction molecules and immune effectors, were identified in Zhikong scallop Chlamys farreri via assembling and screening public available transcriptomic data and expression sequence tags (ESTs). These identified TLR signaling pathway components were constitutively expressed and detectable in various tissues, and almost all of them were highly expressed in gill and hepatopancreas. These results indicated the presence of TLR signaling pathways in both MyD88-dependent and MyD88-independent forms in scallop, and implied the diversified TLR signaling pathway in mollusk C. farreri. |
| Keyword | Chlamys farreri Innate immunity TLR signaling pathway |
| DOI | 10.1016/j.fsi.2017.12.064 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[31530069] ; National Natural Science Foundation of China[41306156] ; AoShan Talents Cultivation Program ; Qingdao National Laboratory for Marine Science and Technology[2017ASTCP-OS13] ; Modern Agro-industry Technology Research System[CARS-49] ; National Natural Science Foundation of China[31530069] ; National Natural Science Foundation of China[41306156] ; AoShan Talents Cultivation Program ; Qingdao National Laboratory for Marine Science and Technology[2017ASTCP-OS13] ; Modern Agro-industry Technology Research System[CARS-49] |
| WOS Research Area | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| WOS Subject | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| WOS ID | WOS:000427344200022 |
| Publisher | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/158388 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Song, Linsheng |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Funct Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China 3.Dalian Ocean Univ, Liaoning Key Lab Marine Anim Immunol, Dalian 116023, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| First Author Affilication | Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Wang, Mengqiang,Wang, Lingling,Jia, Zhihao,et al. The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri[J]. FISH & SHELLFISH IMMUNOLOGY,2018,74:205-212. |
| APA | Wang, Mengqiang,Wang, Lingling,Jia, Zhihao,Yi, Qilin,&Song, Linsheng.(2018).The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri.FISH & SHELLFISH IMMUNOLOGY,74,205-212. |
| MLA | Wang, Mengqiang,et al."The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri".FISH & SHELLFISH IMMUNOLOGY 74(2018):205-212. |
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| The various componen（686KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View | |
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