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| Simpterpenoid A, a Meroterpenoid with a Highly Functionalized Cyclohexadiene Moiety Featuring gem-Propane-1,2-dione and Methylformate Groups, from the Mangrove-Derived Penicillium simplicissimum MA-332 | |
Li, Hong-Lei1 ; Xu, Rui1,2; Li, Xiao-Ming1; Yang, Sui-Qun1; Meng, Ling-Hong1; Wang, Bin-Gui1
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| 2018-03-02 | |
| 发表期刊 | ORGANIC LETTERS
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| ISSN | 1523-7060 |
| 卷号 | 20期号:5页码:1465-1468 |
| 通讯作者 | Li, Xiao-Ming(lixmqdio@126.com) ; Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) |
| 摘要 | Simpterpenoid A (1), an unprecedented meroterpenoid possessing a highly functionalized cyclohexadiene moiety (ring C) featuring gem-propane-1,2-dione and methylformate groups, was characterized from mangrove-derived Penicillium simplicissimum MA-332. Due to the highly oxygenated and functionalized ring C and lack of some key correlations, the unambiguous assignment of the planar structure and steric configuration was solved by X-ray crystallographic analysis. Compound 1 exhibited inhibitory activity against influenza neuraminidase in nanomolar quantities. |
| DOI | 10.1021/acs.orglett.8b00327 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | Natural Science Foundation of China[31570356] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar Project from Shandong Province of China ; Natural Science Foundation of China[31570356] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar Project from Shandong Province of China |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| WOS记录号 | WOS:000426804200049 |
| 出版者 | AMER CHEMICAL SOC |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/158129 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Li, Xiao-Ming; Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Inst Oceanol, Key Lab Expt Marine Biol,Lab Marine Biol & Biotec, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Heze Univ, Dept Life Sci, Daxue Rd 2269, Heze 274015, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 通讯作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Li, Hong-Lei,Xu, Rui,Li, Xiao-Ming,et al. Simpterpenoid A, a Meroterpenoid with a Highly Functionalized Cyclohexadiene Moiety Featuring gem-Propane-1,2-dione and Methylformate Groups, from the Mangrove-Derived Penicillium simplicissimum MA-332[J]. ORGANIC LETTERS,2018,20(5):1465-1468. |
| APA | Li, Hong-Lei,Xu, Rui,Li, Xiao-Ming,Yang, Sui-Qun,Meng, Ling-Hong,&Wang, Bin-Gui.(2018).Simpterpenoid A, a Meroterpenoid with a Highly Functionalized Cyclohexadiene Moiety Featuring gem-Propane-1,2-dione and Methylformate Groups, from the Mangrove-Derived Penicillium simplicissimum MA-332.ORGANIC LETTERS,20(5),1465-1468. |
| MLA | Li, Hong-Lei,et al."Simpterpenoid A, a Meroterpenoid with a Highly Functionalized Cyclohexadiene Moiety Featuring gem-Propane-1,2-dione and Methylformate Groups, from the Mangrove-Derived Penicillium simplicissimum MA-332".ORGANIC LETTERS 20.5(2018):1465-1468. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Simpterpenoid A, a M（1290KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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