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Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14
Cui, Chuan-Ming1,2; Li, Xiao-Ming1; Li, Chun-Shun1; Proksch, Peter3; Wang, Bin-Gui1
2010-04-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号73期号:4页码:729-733
文章类型Article
摘要Cytoglobosins A-G (1-7), seven new cytochalasan derivatives, along with two structurally related known compounds, isochaetoglobosin D (8) and chaetoglobosin F(ex) (9), were isolated and identified from the cultures of Chaetomium globosum QEN-14, an endophytic fungus derived from the marine green alga Ulva pertusa. The structures of the new natural products as well as their relative configurations were elucidated on the basis of 1D and 2D NMR spectra (COSY, HSQC, HMBC, and NOESY) and HRESIMS data. Cytoglobosins C and D (3 and 4) displayed cytotoxic activity against the A-549 tumor cell line.; Financial support from the Ministry of Science and Technology of China (2010CB833802 and 2007AA09Z446) and from the National Science Foundation of China (30910103914) is gratefully acknowledged.
DOI10.1021/np900569t
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收录类别SCI ; IC
语种英语
WOS记录号WOS:000276950000043
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被引频次:119[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/1573
专题实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Univ Dusseldorf, Inst Pharmazeut Biol & Biotechnol, D-40225 Dusseldorf, Germany
第一作者单位中国科学院海洋研究所
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GB/T 7714
Cui, Chuan-Ming,Li, Xiao-Ming,Li, Chun-Shun,et al. Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(4):729-733.
APA Cui, Chuan-Ming,Li, Xiao-Ming,Li, Chun-Shun,Proksch, Peter,&Wang, Bin-Gui.(2010).Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14.JOURNAL OF NATURAL PRODUCTS,73(4),729-733.
MLA Cui, Chuan-Ming,et al."Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14".JOURNAL OF NATURAL PRODUCTS 73.4(2010):729-733.
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