Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14 | |
Cui, Chuan-Ming1,2; Li, Xiao-Ming1; Li, Chun-Shun1; Proksch, Peter3; Wang, Bin-Gui1 | |
2010-04-01 | |
发表期刊 | JOURNAL OF NATURAL PRODUCTS |
ISSN | 0163-3864 |
卷号 | 73期号:4页码:729-733 |
文章类型 | Article |
摘要 | Cytoglobosins A-G (1-7), seven new cytochalasan derivatives, along with two structurally related known compounds, isochaetoglobosin D (8) and chaetoglobosin F(ex) (9), were isolated and identified from the cultures of Chaetomium globosum QEN-14, an endophytic fungus derived from the marine green alga Ulva pertusa. The structures of the new natural products as well as their relative configurations were elucidated on the basis of 1D and 2D NMR spectra (COSY, HSQC, HMBC, and NOESY) and HRESIMS data. Cytoglobosins C and D (3 and 4) displayed cytotoxic activity against the A-549 tumor cell line.; Financial support from the Ministry of Science and Technology of China (2010CB833802 and 2007AA09Z446) and from the National Science Foundation of China (30910103914) is gratefully acknowledged. |
DOI | 10.1021/np900569t |
URL | 查看原文 |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000276950000043 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/1573 |
专题 | 实验海洋生物学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Univ Dusseldorf, Inst Pharmazeut Biol & Biotechnol, D-40225 Dusseldorf, Germany |
第一作者单位 | 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Cui, Chuan-Ming,Li, Xiao-Ming,Li, Chun-Shun,et al. Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(4):729-733. |
APA | Cui, Chuan-Ming,Li, Xiao-Ming,Li, Chun-Shun,Proksch, Peter,&Wang, Bin-Gui.(2010).Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14.JOURNAL OF NATURAL PRODUCTS,73(4),729-733. |
MLA | Cui, Chuan-Ming,et al."Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14".JOURNAL OF NATURAL PRODUCTS 73.4(2010):729-733. |
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