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Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501
Li, Hong-Lei1,2; Li, Xiao-Ming1; Li, Xin1,2; Wang, Chen-Yin3; Liu, Hui1,2; Kassack, Matthias U.3; Meng, Ling-Hong1; Wang, Bin-Gui1
2017
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号80期号:1页码:162-168
通讯作者Kassack, Matthias U.(Matthias.Kassack@uni-duesseldorf.de) ; Meng, Ling-Hong(menglh@ms.qdio.ac.cn) ; Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
摘要Five new polyhydroxylated hydroanthraquinone derivatives, namely, 8-hydroxyconiothyrinone B (1), 8,11-dihydroxyconiothyrinone B (2), 4R,8-dihydroxyconiothyrinone B (3), 4S,8-dihydroxyconiothyrinone B (4), and 4S,8-dihydroxy-10-O-methyldendryol E (5), were isolated and identified from the culture extract of Talaromyces islandicus EN-501, an endophytic fungus obtained from the inner tissue of the marine red alga Laurencia okamurai. The structures of these compounds were established on the basis of detailed interpretation of their NMR and mass spectroscopic data, and the structures and absolute configurations of compounds 1 and 2 were confirmed by X-ray crystallographic analysis, while the absolute configurations of compounds 3-5 were determined by TDDFT calculations of the ECD spectra. The antimicrobial, antioxidant, and cytotoxic activities of compounds 1-5 were evaluated.
DOI10.1021/acs.jnatprod.6b00797
收录类别SCI
语种英语
资助项目Natural Science Foundation of China[31330009] ; Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Taishan Scholar Project from Shandong Province of China ; Bundesminsterium fur Forschung (BMBF, Germany)[BMBF-16GW0108] ; Natural Science Foundation of China[31330009] ; Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Taishan Scholar Project from Shandong Province of China ; Bundesminsterium fur Forschung (BMBF, Germany)[BMBF-16GW0108]
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000393089600022
出版者AMER CHEMICAL SOC
引用统计
被引频次:47[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/157267
专题实验海洋生物学重点实验室
通讯作者Kassack, Matthias U.; Meng, Ling-Hong; Wang, Bin-Gui
作者单位1.Chinese Acad Sci, Lab Marine Biol & Biotechnol, Qmgdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol,Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China
3.Heinrich Heine Univ Dusseldorf, Inst Pharmazeut & Med Chem, Univ Str 1, D-40225 Dusseldorf, Germany
第一作者单位中国科学院海洋研究所
通讯作者单位中国科学院海洋研究所
推荐引用方式
GB/T 7714
Li, Hong-Lei,Li, Xiao-Ming,Li, Xin,et al. Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501[J]. JOURNAL OF NATURAL PRODUCTS,2017,80(1):162-168.
APA Li, Hong-Lei.,Li, Xiao-Ming.,Li, Xin.,Wang, Chen-Yin.,Liu, Hui.,...&Wang, Bin-Gui.(2017).Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501.JOURNAL OF NATURAL PRODUCTS,80(1),162-168.
MLA Li, Hong-Lei,et al."Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501".JOURNAL OF NATURAL PRODUCTS 80.1(2017):162-168.
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