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Tetranorlabdane Diterpenoids from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310
Li, Xiao-Dong1,2; Li, Xin1,2; Li, Xiao-Ming1; Xu, Gang-Ming1; Zhang, Peng1,2; Meng, Ling-Hong1,2; Wang, Bin-Gui1
2016-06-01
Source PublicationPLANTA MEDICA
ISSN0032-0943
Volume82Issue:9-10Pages:877-881
Corresponding AuthorWang, Bin-Gui(wangbg@ms.qdio.ac.cn)
AbstractTwo new tetranorlabdane diterpenoids, asperolides D (1) and E (2), along with six related known congeners (3-8), were isolated and identified from the culture extract of the deep sea sediment-derived fungus Aspergillus wentii SD-310. The structures of these compoundswere established on the basis of spectroscopic interpretation, and the skeleton and absolute configurations of asperolides D (1) and E (2) were determined by X-ray crystallographic analysis. Compounds 1 and 2 were evaluated for their cytotoxic activity against seven tumor cell lines and antibacterial activity against two human and eight aquatic pathogens.
KeywordAspergillus wentii Trichocomaceae marine-derived fungus tetranorlabdane diterpenoids cytotoxic activity antibacterial activity
DOI10.1055/s-0042-102965
Indexed BySCI
Language英语
Funding ProjectMinistry of Science and Technology of China[2012AA092104] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1406402]
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000378913600013
PublisherGEORG THIEME VERLAG KG
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/157252
Collection实验海洋生物学重点实验室
Corresponding AuthorWang, Bin-Gui
Affiliation1.Chinese Acad Sci, Lab Marine Biol & Biotechnol, Qingdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol,Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Li, Xiao-Dong,Li, Xin,Li, Xiao-Ming,et al. Tetranorlabdane Diterpenoids from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310[J]. PLANTA MEDICA,2016,82(9-10):877-881.
APA Li, Xiao-Dong.,Li, Xin.,Li, Xiao-Ming.,Xu, Gang-Ming.,Zhang, Peng.,...&Wang, Bin-Gui.(2016).Tetranorlabdane Diterpenoids from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310.PLANTA MEDICA,82(9-10),877-881.
MLA Li, Xiao-Dong,et al."Tetranorlabdane Diterpenoids from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310".PLANTA MEDICA 82.9-10(2016):877-881.
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