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Optofluidic differential colorimetry for rapid nitrite determination
Shi, Y.1,2; Liu, H. L.1; Zhu, X. Q.1,2; Zhu, J. M.1; Zuo, Y. F.1,2; Yang, Y.1,2; Jiang, F. H.3; Sun, C. J.3; Zhao, W. H.4; Han, X. T.4
Source PublicationLAB ON A CHIP
Corresponding AuthorYang, Y.(
AbstractNitrite detection plays a very important role in environmental monitoring and for industrial purposes. The commonly used colorimetric analysis requires the measurement of a system's calibration curve by asynchronously preparing and detecting a dozen standard samples, leading to time-consuming, slow and cumbersome procedures. Here, we present a differential colorimetry method that determines the nitrite level based on the paired chromaticity gradient, formed by coupling the colour reaction into the microfluidic network. The two gradients reshape each other and contain enough information for the quantitative analysis of the sample being tested, without the need for a calibration curve. The independence of the two gradients of the absorbance change caused by the detecting system and water quality results in a high stability and anti-interference performance, with the assistance of its self-correcting ability. This differential colorimetry method requires little time and energy consumption as only one sample is needed. Standard nitrite solutions of 0.50 mM and 0.33 mM have been determined with an error of 1.16% and 0.50%, respectively. These measurements are advantageous in terms of greater stability by up to 10 times and accuracy by 6 times, compared with the calibration curve approaches. It is foreseeable that this differential colorimetry method will find a wide range of applications in the field of chemical detection.
Indexed BySCI
Funding ProjectNational Natural Science Foundation of China[11774274] ; Foundation Research Fund of Shenzhen Science and Technology Program[JCYJ20170818112939064] ; Qingdao National Laboratory for Marine Science and Technology[QNLM2016ORP0410] ; State Oceanic Administration, People's Republic of China 'marine environmental monitoring and upgrading'
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics
WOS SubjectBiochemical Research Methods ; Chemistry, Multidisciplinary ; Chemistry, Analytical ; Nanoscience & Nanotechnology
WOS IDWOS:000448415500011
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Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorYang, Y.
Affiliation1.Wuhan Univ, Sch Phys & Technol, Minist Educ, Key Lab Artificial Micro & Nanostruct, Wuhan 430072, Hubei, Peoples R China
2.Wuhan Univ, Shenzhen Res Inst, Shenzhen 518000, Peoples R China
3.SOA, Inst Oceanog 1, Beijing, Peoples R China
4.Chinese Acad Sci, Inst Oceanol, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Shi, Y.,Liu, H. L.,Zhu, X. Q.,et al. Optofluidic differential colorimetry for rapid nitrite determination[J]. LAB ON A CHIP,2018,18(19):2994-3002.
APA Shi, Y..,Liu, H. L..,Zhu, X. Q..,Zhu, J. M..,Zuo, Y. F..,...&Han, X. T..(2018).Optofluidic differential colorimetry for rapid nitrite determination.LAB ON A CHIP,18(19),2994-3002.
MLA Shi, Y.,et al."Optofluidic differential colorimetry for rapid nitrite determination".LAB ON A CHIP 18.19(2018):2994-3002.
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