IOCAS-IR  > 海洋生态与环境科学重点实验室
Transcriptome analysis provides insights into the mechanism of albinism during different pigmentation stages of the albino sea cucumber Apostichopus japonicus
Xing, Lili1,2,3; Sun, Lina1,2; Liu, Shilin1,2; Li, Xiaoni1,2,3; Zhang, Libin1,2; Yang, Hongsheng1,2
2018-02-03
发表期刊AQUACULTURE
卷号486页码:148-160
文章类型Article
摘要The sea cucumber Apostichopus japonicus (Selenka), which has nutritive and medical properties, is considered the most valuable commercial marine species in many parts of Asia. Of the different color morphs, the albino sea cucumber is rare and has great appeal to consumers. Identification of factors contributing to albinism in the sea cucumber is therefore likely to provide a scientific basis for improving the cultivability of this morph. In this study, illumina sequencing was performed on three pigmentation stages of the albino sea cucumber: the early pigmentation stage (Wa), the mid pigmentation stage (Wb) and the late pigmentation stage (Wc). In total, 120,365 unigenes were generated with an N50 length of 3360 bp and 60,224 unigenes were annotated from seven functional databases (NR, NT, GO, COG, KEGG, Swissprot and Interpro). In addition, 39,285 SSRs were detected, distributed on 26,156 unigenes. Compared with sea cucumbers during the early pigmentation stage, 842 genes were identified as differentially expressed in the body wall of albino sea cucumbers during the mid-pigmentation stage, including 331 upregulated and 511 downregulated genes. Additionally, compared with sea cucumbers in the mid-pigmentation stage, 247 genes were identified as differentially expressed in the body wall of albino sea cucumbers during the late-pigmentation stage, including 67 upregulated and 180 downregulated genes. GO and KEGG analyses revealed possible differentially expressed genes, including "melanogenesis", "Rassignaling pathway", "cAMP signaling pathway" and "epithelium development" involved in albinism formation in albino sea cucumbers. In conclusion, these studies identified many candidate albinism-related and pigmentation-related genes and signaling pathways. In addition, a comparative analysis was conducted of the differentially expressed genes from albino sea cucumber body walls in different pigmentation stages. The results should be highly useful in further elucidating the mechanisms underlying albinism in sea cucumbers.
关键词Albino Sea Cucumber Pigmentation Stage Transcriptome Albinism-related Genes
DOI10.1016/j.aquaculture.2017.12.016
收录类别SCI
语种英语
WOS记录号WOS:000425875900020
引用统计
文献类型期刊论文
版本出版稿
条目标识符http://ir.qdio.ac.cn/handle/337002/154359
专题海洋生态与环境科学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Xing, Lili,Sun, Lina,Liu, Shilin,et al. Transcriptome analysis provides insights into the mechanism of albinism during different pigmentation stages of the albino sea cucumber Apostichopus japonicus[J]. AQUACULTURE,2018,486:148-160.
APA Xing, Lili,Sun, Lina,Liu, Shilin,Li, Xiaoni,Zhang, Libin,&Yang, Hongsheng.(2018).Transcriptome analysis provides insights into the mechanism of albinism during different pigmentation stages of the albino sea cucumber Apostichopus japonicus.AQUACULTURE,486,148-160.
MLA Xing, Lili,et al."Transcriptome analysis provides insights into the mechanism of albinism during different pigmentation stages of the albino sea cucumber Apostichopus japonicus".AQUACULTURE 486(2018):148-160.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Transcriptome analys(1353KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Xing, Lili]的文章
[Sun, Lina]的文章
[Liu, Shilin]的文章
百度学术
百度学术中相似的文章
[Xing, Lili]的文章
[Sun, Lina]的文章
[Liu, Shilin]的文章
必应学术
必应学术中相似的文章
[Xing, Lili]的文章
[Sun, Lina]的文章
[Liu, Shilin]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Transcriptome analysis provides insights into the mechanism of albinism during different pigmentation stages of the albino sea cucumber.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。