Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas | |
Song, Kai1,2,3; Li, Yingxiang1,2,4; Huang, Baoyu1,2,4; Li, Li1,2,3; Zhang, Guofan1,2,4 | |
2017-12-01 | |
发表期刊 | DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY |
卷号 | 77页码:17-22 |
文章类型 | Article |
摘要 | The invertebrate innate immune system functions in immune defence and the stress response. However, knowledge of the genetic and evolutionary patterns of innate immune genes in Mollusca is limited, especially for oysters. Such information would help clarify how oysters adapt to pathogen-rich environments. Here, we characterized the genetic and evolutionary patterns of the innate immune genes in Crassostrea gigas, using population diversity analysis and evolution rates comparison. Innate immune genes have higher median nucleotide diversity than non-immune genes. Nucleotide diversity varied with functional regions and different immune-related gene families. Evolutionary analysis of two Crassostrea species showed that the innate immune genes are less conserved and have higher rates of evolution in C gigas. We also noted a positive association between nucleotide diversity and selective pressures for genes having orthologues. Our findings will help determine the evolutionary patterns of innate immune genes and the association of these genes with mollusc immunity. (C) 2017 Elsevier Ltd. All rights reserved. |
关键词 | Evolution Pattern Innate Immune Gene Nucleotide Diversity Crassostrea Gigas Oyster |
DOI | 10.1016/j.dci.2017.07.012 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000413387100002 |
引用统计 | |
文献类型 | 期刊论文 |
版本 | 出版稿 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/143232 |
专题 | 实验海洋生物学重点实验室 海洋生物技术研发中心 |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China 2.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Shandong, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266071, Shandong, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Shandong, Peoples R China |
第一作者单位 | 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Song, Kai,Li, Yingxiang,Huang, Baoyu,et al. Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas[J]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,2017,77:17-22. |
APA | Song, Kai,Li, Yingxiang,Huang, Baoyu,Li, Li,&Zhang, Guofan.(2017).Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas.DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,77,17-22. |
MLA | Song, Kai,et al."Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas".DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 77(2017):17-22. |
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文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Genetic and evolutio(558KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 |
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