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Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas
Song, Kai1,2,3; Li, Yingxiang1,2,4; Huang, Baoyu1,2,4; Li, Li1,2,3; Zhang, Guofan1,2,4
2017-12-01
Source PublicationDEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
Volume77Pages:17-22
SubtypeArticle
AbstractThe invertebrate innate immune system functions in immune defence and the stress response. However, knowledge of the genetic and evolutionary patterns of innate immune genes in Mollusca is limited, especially for oysters. Such information would help clarify how oysters adapt to pathogen-rich environments. Here, we characterized the genetic and evolutionary patterns of the innate immune genes in Crassostrea gigas, using population diversity analysis and evolution rates comparison. Innate immune genes have higher median nucleotide diversity than non-immune genes. Nucleotide diversity varied with functional regions and different immune-related gene families. Evolutionary analysis of two Crassostrea species showed that the innate immune genes are less conserved and have higher rates of evolution in C gigas. We also noted a positive association between nucleotide diversity and selective pressures for genes having orthologues. Our findings will help determine the evolutionary patterns of innate immune genes and the association of these genes with mollusc immunity. (C) 2017 Elsevier Ltd. All rights reserved.
KeywordEvolution Pattern Innate Immune Gene Nucleotide Diversity Crassostrea Gigas Oyster
DOI10.1016/j.dci.2017.07.012
Indexed BySCI
Language英语
WOS IDWOS:000413387100002
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.qdio.ac.cn/handle/337002/143232
Collection实验海洋生物学重点实验室
海洋生物技术研发中心
Affiliation1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China
2.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Shandong, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266071, Shandong, Peoples R China
4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Shandong, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Song, Kai,Li, Yingxiang,Huang, Baoyu,et al. Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas[J]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,2017,77:17-22.
APA Song, Kai,Li, Yingxiang,Huang, Baoyu,Li, Li,&Zhang, Guofan.(2017).Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas.DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,77,17-22.
MLA Song, Kai,et al."Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas".DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 77(2017):17-22.
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