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题名: A novel multifunctional electrochemical platform for simultaneous detection, elimination, and inactivation of pathogenic bacteria based on the Vancomycin-functionalised AgNPs/3D-ZnO nanorod arrays
作者: Yang, Zhiqing1,2; Wang, Yi1,3; Zhang, Dun1,3
刊名: BIOSENSORS & BIOELECTRONICS
出版日期: 2017-12-15
卷号: 98, 页码:248-253
关键词: Multifunctional electrochemical platform ; Pathogenic bacteria ; AgNPs/3D-ZnO nanorods arrays ; Vancomycin ; Antibacterial
DOI: 10.1016/j.bios.2017.06.058
文章类型: Article
英文摘要: A novel fast, sensitive, and specific multifunctional electrochemical platform has been proposed for simultaneous detection, elimination, and inactivation of pathogenic bacteria for the first time. The platform is constituted with three-dimensional ZnO nanorod arrays (3D-ZnO) decorated with sliver nanoparticles (AgNPs) and functionalized with vancomycin (Van). Based on the specific recognition of Van for Gram-positive bacteria, the fabricated electrochemical platform has presented high detection sensitivity to Staphylococcus aureus with a low detection limit of 330 cfu/mL and adaptable bacterial-elimination efficiency (50%) at low concentrations (1000-2000 cfu/mL). Moreover, the platform has shown high antibacterial activity (99.99%) arising from the synergistic germicidal effect of the composited antibacterial AgNPs and Van units. The current work could provide new strategies to construct advanced platforms for simultaneous detection, elimination, and inactivation of various pathogenic bacteria.
收录类别: SCI
语种: 英语
WOS记录号: WOS:000407538300035
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.qdio.ac.cn/handle/337002/143105
Appears in Collections:海洋腐蚀与防护研究发展中心_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, 7 Nanhai Rd, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, 19 Jia Yuquan Rd, Beijing 100039, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Open Studio Marine Corros & Protect, 1 Wenhai Rd, Qingdao 266237, Peoples R China

Recommended Citation:
Yang, Zhiqing,Wang, Yi,Zhang, Dun. A novel multifunctional electrochemical platform for simultaneous detection, elimination, and inactivation of pathogenic bacteria based on the Vancomycin-functionalised AgNPs/3D-ZnO nanorod arrays[J]. BIOSENSORS & BIOELECTRONICS,2017,98:248-253.
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文件名: A novel multifunctional electrochemical platform for simultaneous detection, elimination, and inactivation of pathogenic bacteria.pdf
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