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| A novel multifunctional electrochemical platform for simultaneous detection, elimination, and inactivation of pathogenic bacteria based on the Vancomycin-functionalised AgNPs/3D-ZnO nanorod arrays | |
Yang, Zhiqing1,2; Wang, Yi1,3 ; Zhang, Dun1,3
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| 2017-12-15 | |
| 发表期刊 | BIOSENSORS & BIOELECTRONICS
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| 卷号 | 98页码:248-253 |
| 文章类型 | Article |
| 摘要 | A novel fast, sensitive, and specific multifunctional electrochemical platform has been proposed for simultaneous detection, elimination, and inactivation of pathogenic bacteria for the first time. The platform is constituted with three-dimensional ZnO nanorod arrays (3D-ZnO) decorated with sliver nanoparticles (AgNPs) and functionalized with vancomycin (Van). Based on the specific recognition of Van for Gram-positive bacteria, the fabricated electrochemical platform has presented high detection sensitivity to Staphylococcus aureus with a low detection limit of 330 cfu/mL and adaptable bacterial-elimination efficiency (50%) at low concentrations (1000-2000 cfu/mL). Moreover, the platform has shown high antibacterial activity (99.99%) arising from the synergistic germicidal effect of the composited antibacterial AgNPs and Van units. The current work could provide new strategies to construct advanced platforms for simultaneous detection, elimination, and inactivation of various pathogenic bacteria. |
| 关键词 | Multifunctional Electrochemical Platform Pathogenic Bacteria Agnps/3d-zno Nanorods Arrays Vancomycin Antibacterial |
| DOI | 10.1016/j.bios.2017.06.058 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000407538300035 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 版本 | 出版稿 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/143105 |
| 专题 | 海洋环境腐蚀与生物污损重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, 19 Jia Yuquan Rd, Beijing 100039, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Open Studio Marine Corros & Protect, 1 Wenhai Rd, Qingdao 266237, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Yang, Zhiqing,Wang, Yi,Zhang, Dun. A novel multifunctional electrochemical platform for simultaneous detection, elimination, and inactivation of pathogenic bacteria based on the Vancomycin-functionalised AgNPs/3D-ZnO nanorod arrays[J]. BIOSENSORS & BIOELECTRONICS,2017,98:248-253. |
| APA | Yang, Zhiqing,Wang, Yi,&Zhang, Dun.(2017).A novel multifunctional electrochemical platform for simultaneous detection, elimination, and inactivation of pathogenic bacteria based on the Vancomycin-functionalised AgNPs/3D-ZnO nanorod arrays.BIOSENSORS & BIOELECTRONICS,98,248-253. |
| MLA | Yang, Zhiqing,et al."A novel multifunctional electrochemical platform for simultaneous detection, elimination, and inactivation of pathogenic bacteria based on the Vancomycin-functionalised AgNPs/3D-ZnO nanorod arrays".BIOSENSORS & BIOELECTRONICS 98(2017):248-253. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| A novel multifunctio（747KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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