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Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1)
Zhao, Wei1,3; Wang, Lei1,2; Liu, Mei1,2; Jiang, Keyong1,2; Wang, Mengqiang1,2; Yang, Guang3; Qi, Cancan1,2; Wang, Baojie1,2
2017-09-01
发表期刊DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
卷号74页码:69-81
文章类型Article
摘要Aflatoxin produced by Aspergillus flavus or Aspergillus parasiticus fungi during grain and feed processing and storage. Aflatoxins cause severe health problems reducing the yield and profitability of shrimp cultures. We sought to understand the interaction between shrimp immunity and aflatoxin B1 (AFB1), analyzing transcriptome expression, antioxidant enzyme activity, and histological features of the hepatopancreas of shrimp fed with AFB1. From over 4 million high-quality reads, de novo unigene assembly produced 103,644 fully annotated genes. A total of 1024 genes were differentially expressed in shrimp fed with AFB1, being involved in functions, such as peroxidase metabolism, signal transduction, transcriptional control, apoptosis, proteolysis, endocytosis, and cell adhesion and cell junction. Upon AFB1 challenge, there were severe histological alterations in shrimp hepatopancreas. AFB1 challenge increased the activity of several antioxidant enzymes. Our data contribute to improve the current understanding of host-AFB1 interaction, providing an abundant source for identification of novel genes. (C) 2017 Elsevier Ltd. All rights reserved.
关键词Litopenaeus Vannamei Hepatopancreas Aflatoxin B1 Transcriptome Enzyme Activity Histopathology
DOI10.1016/j.dci.2017.03.031
收录类别SCI
语种英语
WOS记录号WOS:000403512600009
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.qdio.ac.cn/handle/337002/137148
专题实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China
3.Tianjin Agr Univ, Coll Fishery Sci, Tianjin Key Lab Aquaculture, Tianjin 300384, Peoples R China
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Zhao, Wei,Wang, Lei,Liu, Mei,et al. Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1)[J]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,2017,74:69-81.
APA Zhao, Wei.,Wang, Lei.,Liu, Mei.,Jiang, Keyong.,Wang, Mengqiang.,...&Wang, Baojie.(2017).Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1).DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,74,69-81.
MLA Zhao, Wei,et al."Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1)".DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 74(2017):69-81.
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