Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation | |
Li, Kecheng1,2; Xing, Ronge1; Liu, Song1; Qin, Yukun1; Li, Pengcheng1 | |
2017 | |
发表期刊 | BIOMED RESEARCH INTERNATIONAL |
文章类型 | Article |
摘要 | Chitohexaose has attracted wide interest due to its special bioactivities and these potential activities are significantly related to N-acetylation. Herein, six chitohexaose fractions with different degrees of acetylation were prepared by selective N-acetylation and ion-exchange chromatography and further analyzed by ESI/MS. It is revealed that all the six N-acetylated chitohexaoses were of single molecular weight, the molecular weights of which were exactly assigned to 1026.44 Da, 1068.44 Da, 1110.48 Da, 1152.48 Da, 1194.49 Da, and 1236.48 Da, respectively. These results suggested that the six prepared N-acetylated chitohexaoses were N-acetylchitohexaose (D5A1), di-N-acetylchitohexaose (D4A2), tri-N-acetylchitohexaose (D3A3), tetra-N-acetylchitohexaose (D2A4), penta-N-acetylchitohexaose (D1A5), and hexa-N-acetylchitohexaose (A6), respectively, which are of great significance to screen their bioactivities and discover well-defined chitooligosaccharide molecules as potential drugs. |
DOI | 10.1155/2017/2486515 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000402657100001 |
引用统计 | |
文献类型 | 期刊论文 |
版本 | 出版稿 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/137099 |
专题 | 海洋生物技术研发中心 |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.IOCAS, Nantong Marine Sci & Technol R&D Ctr, Nantong 226006, Jiangsu, Peoples R China |
第一作者单位 | 实验海洋生物学重点实验室; 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Li, Kecheng,Xing, Ronge,Liu, Song,et al. Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation[J]. BIOMED RESEARCH INTERNATIONAL,2017. |
APA | Li, Kecheng,Xing, Ronge,Liu, Song,Qin, Yukun,&Li, Pengcheng.(2017).Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation.BIOMED RESEARCH INTERNATIONAL. |
MLA | Li, Kecheng,et al."Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation".BIOMED RESEARCH INTERNATIONAL (2017). |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Access to N-Acetylat(4378KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论