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Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review
Wang, Bao-Cheng1,2; Wang, Li-Jun1; Jiang, Bo1; Wang, Shuai-Yu1; Wu, Ning1; Li, Xiang-Qian1; Shi, Da-Yong1,2,3
2017
Source PublicationMINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume17Issue:8Pages:683-692
SubtypeReview
AbstractBackground: The widespread application of fluorine in drug design benefits from distinctive properties. Incorporation of fluorine can positively modulate certain pharmacokinetics properties, including lipophilicity, eletrophilicity, metabolic stability, chemical stability, et al., which were of interest to medicinal chemists. Herein, fluorinated compounds, which have been designed and evaluated for anticancer, antimicrobial, anti-inflammatory and antivirus activity, et al. during the last 6 years (2010-2015) are summarized.
KeywordApplication Of Fluorine Anticancer Antimicrobial Anti-inflammatory Antivirus Activity Drug Design Importance Of Fluorinated Compounds
DOI10.2174/1389557515666151016124957
Indexed BySCI
Language英语
WOS IDWOS:000402475700005
Citation statistics
Document Type期刊论文
Version出版稿
Identifierhttp://ir.qdio.ac.cn/handle/337002/137080
Collection海洋生物技术研发中心
Affiliation1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266071, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wang, Bao-Cheng,Wang, Li-Jun,Jiang, Bo,et al. Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2017,17(8):683-692.
APA Wang, Bao-Cheng.,Wang, Li-Jun.,Jiang, Bo.,Wang, Shuai-Yu.,Wu, Ning.,...&Shi, Da-Yong.(2017).Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review.MINI-REVIEWS IN MEDICINAL CHEMISTRY,17(8),683-692.
MLA Wang, Bao-Cheng,et al."Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review".MINI-REVIEWS IN MEDICINAL CHEMISTRY 17.8(2017):683-692.
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