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Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review
Wang, Bao-Cheng1,2; Wang, Li-Jun1; Jiang, Bo1; Wang, Shuai-Yu1; Wu, Ning1; Li, Xiang-Qian1; Shi, Da-Yong1,2,3
2017
发表期刊MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷号17期号:8页码:683-692
文章类型Review
摘要Background: The widespread application of fluorine in drug design benefits from distinctive properties. Incorporation of fluorine can positively modulate certain pharmacokinetics properties, including lipophilicity, eletrophilicity, metabolic stability, chemical stability, et al., which were of interest to medicinal chemists. Herein, fluorinated compounds, which have been designed and evaluated for anticancer, antimicrobial, anti-inflammatory and antivirus activity, et al. during the last 6 years (2010-2015) are summarized.
关键词Application Of Fluorine Anticancer Antimicrobial Anti-inflammatory Antivirus Activity Drug Design Importance Of Fluorinated Compounds
DOI10.2174/1389557515666151016124957
收录类别SCI
语种英语
WOS记录号WOS:000402475700005
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.qdio.ac.cn/handle/337002/137080
专题海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266071, Peoples R China
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GB/T 7714
Wang, Bao-Cheng,Wang, Li-Jun,Jiang, Bo,et al. Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2017,17(8):683-692.
APA Wang, Bao-Cheng.,Wang, Li-Jun.,Jiang, Bo.,Wang, Shuai-Yu.,Wu, Ning.,...&Shi, Da-Yong.(2017).Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review.MINI-REVIEWS IN MEDICINAL CHEMISTRY,17(8),683-692.
MLA Wang, Bao-Cheng,et al."Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review".MINI-REVIEWS IN MEDICINAL CHEMISTRY 17.8(2017):683-692.
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