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Effect of the molecular weight of water-soluble chitosan on its fat-/cholesterol-binding capacities and inhibitory activities to pancreatic lipase
Jin, Qiu1,2; Yu, Huahua1; Wang, Xueqin1; Li, Kecheng1; Li, Pengcheng1
2017-05-03
Source PublicationPEERJ
Volume5
SubtypeArticle
AbstractBackground. Obesity has become a worldwide burden to public health in recent decades. Given that obesity is caused by an imbalance between caloric intake and expenditure, and that dietary fat is the most important energy source of all macronutrients (by providing the most calories), a valuable strategy for obesity treatment and prevention is to block fat absorption via the gastrointestinal pathway. In this study, the fat- and cholesterol-binding capacities and the inhibition of pancreatic lipase by water-soluble chitosan (WSC) with different weight-average molecular weight (Mw) were tested and compared in vitro, in order to determine the anti-obesity effects of WSC and the influence of its Mw.
KeywordWater-soluble Chitosan Weight-average Molecular Weight Fat Cholesterol Pancreatic Lipase
DOI10.7717/peerj.3279
Indexed BySCI
Language英语
WOS IDWOS:000400705900007
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.qdio.ac.cn/handle/337002/137049
Collection海洋生物技术研发中心
实验海洋生物学重点实验室
海洋环境工程技术研究发展中心
Affiliation1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Jin, Qiu,Yu, Huahua,Wang, Xueqin,et al. Effect of the molecular weight of water-soluble chitosan on its fat-/cholesterol-binding capacities and inhibitory activities to pancreatic lipase[J]. PEERJ,2017,5.
APA Jin, Qiu,Yu, Huahua,Wang, Xueqin,Li, Kecheng,&Li, Pengcheng.(2017).Effect of the molecular weight of water-soluble chitosan on its fat-/cholesterol-binding capacities and inhibitory activities to pancreatic lipase.PEERJ,5.
MLA Jin, Qiu,et al."Effect of the molecular weight of water-soluble chitosan on its fat-/cholesterol-binding capacities and inhibitory activities to pancreatic lipase".PEERJ 5(2017).
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