IOCAS-IR  > 海洋生物技术研发中心
RestrictionDigest: A powerful Perl module for simulating genomic restriction digests
Wang, Jinpeng1,2,3,5; Li, Li1,4,5; Qi, Haigang1,3,5; Dua, Xuedi1,3,5; Zhang, Guofan1,3,5
2016-05-01
发表期刊ELECTRONIC JOURNAL OF BIOTECHNOLOGY
卷号21页码:36-42
文章类型Article
摘要Background: Reduced-representation sequencing technology is widely used in genotyping for its economical and efficient features. A popular way to construct the reduced-representation sequencing libraries is to digest the genomic DNA with restriction enzymes. A key factor of this method is to determine the restriction enzyme(s). But there are few computer programs which can evaluate the usability of restriction enzymes in reduced-representation sequencing. SimRAD is an R package which can simulate the digestion of DNA sequence by restriction enzymes and return enzyme loci number as well as fragment number. But for linkage mapping analysis, enzyme loci distribution is also an important factor to evaluate the enzyme. For phylogenetic studies, comparison of the enzyme performance across multiple genomes is important. It is strongly needed to develop a simulation tool to implement these functions.
关键词Genotyping Reduced-representation Libraries Reduced-representation Sequencing
DOI10.1016/j.ejbt.2016.02.003
收录类别SCI
语种英语
WOS记录号WOS:000376595900005
引用统计
文献类型期刊论文
版本出版稿
条目标识符http://ir.qdio.ac.cn/handle/337002/131085
专题海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China
4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266071, Peoples R China
5.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714
Wang, Jinpeng,Li, Li,Qi, Haigang,et al. RestrictionDigest: A powerful Perl module for simulating genomic restriction digests[J]. ELECTRONIC JOURNAL OF BIOTECHNOLOGY,2016,21:36-42.
APA Wang, Jinpeng,Li, Li,Qi, Haigang,Dua, Xuedi,&Zhang, Guofan.(2016).RestrictionDigest: A powerful Perl module for simulating genomic restriction digests.ELECTRONIC JOURNAL OF BIOTECHNOLOGY,21,36-42.
MLA Wang, Jinpeng,et al."RestrictionDigest: A powerful Perl module for simulating genomic restriction digests".ELECTRONIC JOURNAL OF BIOTECHNOLOGY 21(2016):36-42.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
RestrictionDigest_ A(510KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang, Jinpeng]的文章
[Li, Li]的文章
[Qi, Haigang]的文章
百度学术
百度学术中相似的文章
[Wang, Jinpeng]的文章
[Li, Li]的文章
[Qi, Haigang]的文章
必应学术
必应学术中相似的文章
[Wang, Jinpeng]的文章
[Li, Li]的文章
[Qi, Haigang]的文章
相关权益政策
暂无数据
收藏/分享
文件名: RestrictionDigest_ A powerful Perl module for simulating genomic restriction digests.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。