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Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp W007
Zhang Hongyu1; Xie Zeping3; Lou Tingting4; Jiang Peng2
2016-03-01
发表期刊CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
卷号34期号:2页码:386-390
文章类型Article
摘要A new isobenzofuran derivative (1) was isolated from the marine Streptomyces sp. W007 and its structure was determined through extensive spectroscopic analyses, including 1D-NMR, 2D-NMR, and ESI-MS. The absolute configuration of compound 1 was determined by a combination of experimental analyses and comparison with reported data, including biogenetic reasoning, J-coupling analysis, NOESY, and H-1-(HCOSY)-H-1. Compound 1 exhibited no cytotoxicity against human cells of gastric cancer BGC-823, lung cancer A549, and breast cancer MCF7.
关键词Marine Streptomycete Isobenzofuran Derivative Absolute Confi Guration Cytotoxicity
DOI10.1007/s00343-015-4326-0
收录类别SCI
语种英语
WOS记录号WOS:000371607000014
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/126191
专题实验海洋生物学重点实验室
作者单位1.Tianjin Univ Commerce, Coll Biotechnol & Food Sci, Tianjin Key Lab Food Biotechnol, Tianjin 300134, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
3.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
4.Tianjin Entry & Exit Inspect & Quarantine Bur, Tianjin 300461, Peoples R China
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Zhang Hongyu,Xie Zeping,Lou Tingting,et al. Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp W007[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2016,34(2):386-390.
APA Zhang Hongyu,Xie Zeping,Lou Tingting,&Jiang Peng.(2016).Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp W007.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,34(2),386-390.
MLA Zhang Hongyu,et al."Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp W007".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 34.2(2016):386-390.
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