Institutional Repository of Key Laboratory of Marine Ecology & Environmental Sciences, CAS
Toxin composition and toxicity dynamics of marine gastropod Nassarius spp. collected from Lianyungang, China | |
Luo, X.1,2; Yu, R. -C.1; Wang, X. -J.1,3; Zhou, M. -J.1; Yu, RC (reprint author), Chinese Acad Sci, Key Lab Marine Ecol & Environm Sci, Inst Oceanol, Qingdao 266071, Peoples R China. | |
2012 | |
发表期刊 | FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT |
ISSN | 1944-0049 |
卷号 | 29期号:1页码:117-127 |
文章类型 | Article |
摘要 | Consumption of nassariid gastropods often leads to poisoning incidents in some coastal provinces in China. To elucidate the pattern of toxicity dynamics and origin of toxins, samples of gastropod Nassarius spp. were collected from late May to early August 2007 from Lianyungang, Jiangsu province, where the poisoning incidents have been frequently reported. Toxicity was first screened with the mouse bioassay method, and tetrodotoxin and its analogues (TTXs) were analysed with high-performance liquid chromatography coupled with an ion-trap mass spectrometer (HPLC-MSn). The toxicity of nassariid N. semiplicatus showed an 'M'-shaped pattern of fluctuation during the sampling season. Two peaks of toxicity appeared in late May and late July. The maximum toxicity was recorded on 24 May, with the value of 846 mouse unit (MU) g(-1) of tissue (wet weight). TTX and its analogues trideoxyTTX, 4-epiTTX, anhydroTTX and oxoTTX were detected in the nassariid samples. TrideoxyTTX but not TTX was the major toxin in all the samples. No paralytic shellfish poison (PSP) was detected in the sample with the maximum toxicity by HPLC-FLD analysis. Variation of TTX content in the tissue of nassariid gastropods correlates well with the dynamics of toxicity. It is suggested that TTXs are the major toxins corresponding to the toxicity of the nassariids, and May and July are the high-risk seasons for consumption of nassariids, which is critical for the management of poisoning incidents. |
关键词 | Seafood Natural Toxicants Chromatography - Lc/ms Bioassay |
学科领域 | Chemistry, Applied ; Food Science & Technology ; Toxicology |
DOI | 10.1080/19440049.2011.615069 |
URL | 查看原文 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000301934300013 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/12454 |
专题 | 海洋生态与环境科学重点实验室 |
通讯作者 | Yu, RC (reprint author), Chinese Acad Sci, Key Lab Marine Ecol & Environm Sci, Inst Oceanol, Qingdao 266071, Peoples R China. |
作者单位 | 1.Chinese Acad Sci, Key Lab Marine Ecol & Environm Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Minist Educ & Shanghai Ocean Univ, Key Lab Aquat Genet Resources Excavat & Utilizat, Shanghai 201306, Peoples R China |
第一作者单位 | 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Luo, X.,Yu, R. -C.,Wang, X. -J.,et al. Toxin composition and toxicity dynamics of marine gastropod Nassarius spp. collected from Lianyungang, China[J]. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT,2012,29(1):117-127. |
APA | Luo, X.,Yu, R. -C.,Wang, X. -J.,Zhou, M. -J.,&Yu, RC .(2012).Toxin composition and toxicity dynamics of marine gastropod Nassarius spp. collected from Lianyungang, China.FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT,29(1),117-127. |
MLA | Luo, X.,et al."Toxin composition and toxicity dynamics of marine gastropod Nassarius spp. collected from Lianyungang, China".FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 29.1(2012):117-127. |
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