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| Therapeutic effect of an injectable sustained-release sinomenine hydrochloride and sodium hyaluronate compound in a rabbit model of osteoarthritis | |
| Liu Wen-guang1,2,3; Ling Pei-xue1; Lin Xiu-kun2; Chen Jian-ying1; Wang Shao-jin3; Li Peng1; Wu Xiao-juan4; Zhao Dong-mei3; Liu Sheng-hou3; Ling, PX (reprint author), Inst Biopharmaceut Shandong Prov, Jinan 250101, Shandong, Peoples R China. | |
| 2012-07-20 | |
| 发表期刊 | CHINESE MEDICAL JOURNAL
 |
| ISSN | 0366-6999 |
| 卷号 | 125期号:14页码:2543-2547 |
| 文章类型 | Article |
| 摘要 | Background While intra-articular injection of sinomenine hydrochloride has a therapeutic effect on osteoarthritis, it has a short half-life, and is thermolabile and photolabile. The aim of this research was to evaluate the sustained-release of sinomenine hydrochloride from an injectable sinomenine hydrochloride and sodium hyaluronate compound (CSSSI) and its therapeutic effect in a rabbit model of osteoarthritis following intra-articular injection. |
| 关键词 | Sinomenine Osteoarthritis Sodium Hyaluronate Articular Cavity Injection |
| 学科领域 | Medicine, General & Internal |
| DOI | 10.3760/cma.j.issn.0366-6999.2012.14.027 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000307677600027 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12400 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Ling, PX (reprint author), Inst Biopharmaceut Shandong Prov, Jinan 250101, Shandong, Peoples R China. |
| 作者单位 | 1.Inst Biopharmaceut Shandong Prov, Jinan 250101, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Shandong, Peoples R China 3.Shandong Univ, Hosp 2, Jinan 250033, Shandong, Peoples R China 4.Shandong Univ, Dept Pathol, Sch Med, Jinan 250014, Shandong, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Liu Wen-guang,Ling Pei-xue,Lin Xiu-kun,et al. Therapeutic effect of an injectable sustained-release sinomenine hydrochloride and sodium hyaluronate compound in a rabbit model of osteoarthritis[J]. CHINESE MEDICAL JOURNAL,2012,125(14):2543-2547. |
| APA | Liu Wen-guang.,Ling Pei-xue.,Lin Xiu-kun.,Chen Jian-ying.,Wang Shao-jin.,...&Ling, PX .(2012).Therapeutic effect of an injectable sustained-release sinomenine hydrochloride and sodium hyaluronate compound in a rabbit model of osteoarthritis.CHINESE MEDICAL JOURNAL,125(14),2543-2547. |
| MLA | Liu Wen-guang,et al."Therapeutic effect of an injectable sustained-release sinomenine hydrochloride and sodium hyaluronate compound in a rabbit model of osteoarthritis".CHINESE MEDICAL JOURNAL 125.14(2012):2543-2547. |
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