Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| A Novel Polypeptide Extracted From Ciona savignyi Induces Apoptosis Through a Mitochondrial-Mediated Pathway in Human Colorectal Carcinoma Cells | |
| Cheng, Linyou1,2; Wang, Chunguang3; Liu, Haizhou1; Wang, Fengxia1; Zheng, Lanhong1; Zhao, Jin1; Chu, Edward4,5; Lin, Xiukun1; Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China. | |
| 2012-09-01 | |
| 发表期刊 | CLINICAL COLORECTAL CANCER
 |
| ISSN | 1533-0028 |
| 卷号 | 11期号:3页码:207-214 |
| 文章类型 | Article |
| 摘要 | An ascidian is a marine animal that is important in the pharmacology field. Many compounds with special bioactivity, especially those with antitumor properties, have been developed from it. We extracted and purified a novel polypeptide with potent antitumor activity from the Ciona savignyi (an ascidian) by chromatography. Our results suggest that the polypeptide is a promising drug candidate for the treatment of cancer. |
| 关键词 | Antitumor Ciona Savignyi Polypeptide Purification And Identification |
| 学科领域 | Oncology |
| DOI | 10.1016/j.dcc.2012.01.002 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000308622400008 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12264 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Acad Pharmaceut Sci, Inst Biopharmaceut Shandong, Jinan, Peoples R China 3.Tongji Univ, Inst Prot Res, Shanghai 200092, Peoples R China 4.Univ Pittsburgh, Inst Canc, Pittsburgh, PA USA 5.Univ Pittsburgh, Med Ctr, Div Hematol Oncol, Pittsburgh, PA USA |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Cheng, Linyou,Wang, Chunguang,Liu, Haizhou,et al. A Novel Polypeptide Extracted From Ciona savignyi Induces Apoptosis Through a Mitochondrial-Mediated Pathway in Human Colorectal Carcinoma Cells[J]. CLINICAL COLORECTAL CANCER,2012,11(3):207-214. |
| APA | Cheng, Linyou.,Wang, Chunguang.,Liu, Haizhou.,Wang, Fengxia.,Zheng, Lanhong.,...&Lin, XK .(2012).A Novel Polypeptide Extracted From Ciona savignyi Induces Apoptosis Through a Mitochondrial-Mediated Pathway in Human Colorectal Carcinoma Cells.CLINICAL COLORECTAL CANCER,11(3),207-214. |
| MLA | Cheng, Linyou,et al."A Novel Polypeptide Extracted From Ciona savignyi Induces Apoptosis Through a Mitochondrial-Mediated Pathway in Human Colorectal Carcinoma Cells".CLINICAL COLORECTAL CANCER 11.3(2012):207-214. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| A Novel Polypeptide （1549KB） | 限制开放 | 使用许可 | 浏览 | |||
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