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Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta)
Qi, Huimin1,2; Huang, Liye3; Liu, Xiaolei4; Liu, Dongmei2; Zhang, Quanbin1; Liu, Shunmei2; Zhang, QB (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
2012-01-15
发表期刊CARBOHYDRATE POLYMERS
ISSN0144-8617
卷号87期号:2页码:1637-1640
文章类型Article
摘要In this study, high sulfate content ulvan (HU) was prepared with sulfur trioxide/N,N-dimethylformamide (SO3-DMF) in formamide, and the antihyperlipidemic activity of ulvan and HU in mice was determined. Obvious differences in antihyperlipidemic activity between natural ulvan and HU were observed, moreover, the antihyperlipidemic activity of HU-fed 250 mg/kg was the strongest, compared to natural ulvan fed group, triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) concentrations were significantly decreased 28.1% (P < 0.05) and 28.4% (P < 0.01), respectively. It was likely that the sulfate content had significant effect on the antihyperlipidemic activity. On the other hand, the results proved that the antihyperlipidemic activity was not concentration dependent for HU-fed mice. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.
关键词Polysaccharide Ulva Pertusa High Sulfate Content Ulvan Antihyperlipidemic Activity
学科领域Chemistry, Applied ; Chemistry, Organic ; Polymer Science
DOI10.1016/j.carbpol.2011.09.073
URL查看原文
收录类别SCI
语种英语
WOS记录号WOS:000298305400092
引用统计
被引频次:101[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/12212
专题海洋生物技术研发中心
通讯作者Zhang, QB (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Weifang Med Univ, Weifang 261053, Peoples R China
3.Shandong Inst Sci & Tech Informat, Jinan 250101, Peoples R China
4.Weifang Univ, Weifang 261061, Peoples R China
第一作者单位中国科学院海洋研究所
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GB/T 7714
Qi, Huimin,Huang, Liye,Liu, Xiaolei,et al. Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta)[J]. CARBOHYDRATE POLYMERS,2012,87(2):1637-1640.
APA Qi, Huimin.,Huang, Liye.,Liu, Xiaolei.,Liu, Dongmei.,Zhang, Quanbin.,...&Zhang, QB .(2012).Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta).CARBOHYDRATE POLYMERS,87(2),1637-1640.
MLA Qi, Huimin,et al."Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta)".CARBOHYDRATE POLYMERS 87.2(2012):1637-1640.
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