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Antitumor Peptides from Marine Organisms
Zheng, Lan-Hong3; Wang, Yue-Jun3; Sheng, Jun3; Wang, Fang3; Zheng, Yuan3; Lin, Xiu-Kun1,2; Sun, Mi3
2011-10-01
发表期刊MARINE DRUGS
ISSN1660-3397
卷号9期号:10页码:1840-1859
文章类型Review
摘要The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.; The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.
关键词Antitumor Peptides Marine Organisms
学科领域Pharmacology & Pharmacy
DOI10.3390/md9101840
URL查看原文
收录类别SCI
语种英语
WOS记录号WOS:000298928300008
引用统计
被引频次:112[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/11783
专题实验海洋生物学重点实验室
作者单位1.Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
3.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China
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GB/T 7714
Zheng, Lan-Hong,Wang, Yue-Jun,Sheng, Jun,et al. Antitumor Peptides from Marine Organisms[J]. MARINE DRUGS,2011,9(10):1840-1859.
APA Zheng, Lan-Hong.,Wang, Yue-Jun.,Sheng, Jun.,Wang, Fang.,Zheng, Yuan.,...&Sun, Mi.(2011).Antitumor Peptides from Marine Organisms.MARINE DRUGS,9(10),1840-1859.
MLA Zheng, Lan-Hong,et al."Antitumor Peptides from Marine Organisms".MARINE DRUGS 9.10(2011):1840-1859.
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